Наличие венозных тромбозов в семье повышает риск флеботромбоза в 15-16 раз:
Of the 846 relatives with thrombophilia (excluding probands), 139 (16%) had experienced a VTE with an incidence of 4.4 per 1000 person years. Of the controls, 15 of the 1212 (1%) controls had experienced a VTE with an incidence of 0.3 per 1000 person years. The risk of venous thrombosis associated with familial thrombophilia was 15.7 (95% CI 9.2-26.8) and remained similar after adjustment for regional and sex-effects (16.4; 95% CI 9.6-28.0).
J Thromb Haemost. 2004 Sep;2(9):1526-32.
Familial thrombophilia and lifetime risk of venous thrombosis.
Vossen CY, Conard J, Fontcuberta J, Makris M, Van Der Meer FJ, Pabinger I, Palareti G, Preston FE, Scharrer I, Souto JC, Svensson P, Walker ID, Rosendaal FR.