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Am. J. Hum. Genet. (in the press)
Male-pattern baldness is a misfortune that men inherit mainly from their mothers.
A systematic survey of the genomes of brothers from 95 families reveals that variability in the androgen receptor gene on the X chromosome is the single most important cause. The research, led by Markus Nöthen of the University of Bonn, Germany, adds to evidence from an earlier investigation of male-pattern baldness that implicated the same gene. As yet, the mechanism remains unclear.
Male-pattern baldness is a misfortune that men inherit mainly from their mothers.
A systematic survey of the genomes of brothers from 95 families reveals that variability in the androgen receptor gene on the X chromosome is the single most important cause. The research, led by Markus Nöthen of the University of Bonn, Germany, adds to evidence from an earlier investigation of male-pattern baldness that implicated the same gene. As yet, the mechanism remains unclear.
Что-то я не пойму, почему эту проблему начали исследовать снова. То, что уровень чувствительности к андрогенам наследуется по принципу "от деда к внуку через мать", меня учили в курсе генетики почти 30 лет назад.
