лимфолейкоз

[otter]

помогает ли fe 59 при хроническом лимфолейкозе стадии 3б

 

[Maxxie]

Могу сказать, что Fe 59 не используется в онкологии нигде в мире. Никаких адекватных исследований в медицинских журналах по применению этого изотопа нет.

По лечению лимфолейкоза же наоборот работ очень много в любом международном медицинском журнале. Fe 59 нигде не фигурирует.

 

[Mars]

P.S. http://www.meb.uni-bonn.de/cancer.gov/CDR0000258005.html#REF_86

http://www.nci.nih.gov/cancertopics/pdq/treatment/CLL/patient

http://www.cancer.org/docroot/cri/cri_2_3x.asp?dt=62



Stage III Chronic Lymphocytic Leukemia

Standard treatment options:



1)Observation in asymptomatic or minimally affected patients.



2)Oral alkylating agents with or without corticosteroids.



3)Fludarabine, 2-chlorodeoxyadenosine, or pentostatin.



4)Combination chemotherapy.

CVP: cyclophosphamide + vincristine + prednisone.

CHOP: cyclophosphamide + doxorubicin + vincristine + prednisone.

Fludarabine + cyclophosphamide.

Fludarabine + chlorambucil.

Fludarabine + rituximab.



5)Splenectomy or splenic irradiation may be helpful in patients with hypersplenism or for patients with the complications of immune-mediated thrombocytopenia or hemolytic anemia who fail to respond to alkylating agents and prednisone.



6)Alemtuzumab (campath-1H) and rituximab (monoclonal antibodies) are under clinical evaluation. Higher doses of rituximab than those used for other non-Hodgkin lymphomas are required.



7)Bone marrow and peripheral stem transplantations are under clinical evaluation.



http://www.nci.nih.gov/cancertopics/pdq/treatment/CLL/HealthProfessional/page7