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Именно так, уважаемая коллега.Чтобы почистить печень, за рекомендациями лучше обращаться не на медицинский форум, а на шарлатанский, там подскажут подробнее.
Я хочу почистить печень,посоветовали КАРСИЛ.Подскажите ,пожалуйста, в течении какого срока нужно пить и нужно ли придерживаться какой-то диеты.
я написала,что прописал врач
Выделение мое. По поводу отравлений грибами читаем, напр., тут:Drug Category: Potentially beneficial medications
The literature is fraught with case studies and trials. Decreases in mortality are likely due to improved supportive care.
Вот здесь еще один обзор по силимарину:Although there are no controlled clinical trials, a few anecdotal studies provide the basis for regimens recommended to treat Amanita poisoning. Use of i.v. penicillin G is supported by most reports. Silibinin, although preferred over penicillin, is not easily available in the United States. In those with acute liver failure, liver transplantation can be life saving.
А вот здесь более свежий систематический обзор с метанализом по клиническому эвиденсу силимарина:We conclude that available evidence suggests that silymarin may play a role in the therapy of (alcoholic) liver cirrhosis. Silymarin is has a good safety record and only rare case reports of gastrointestinal disturbances and allergic skin rashes have been published. This review does not aim to replace future prospective trials aiming to provide the 'final' evidence of the efficacy of silymarin.
А вот здесь мы можем прочесть:CONCLUSIONS: Based on the available clinical evidence it can be concluded - concerning possible risks /probable benefits - that it is reasonable to employ silymarin as a supportive element in the therapy of Amanita phalloides poisoning but also (alcoholic and grade Child 'A') liver cirrhosis. A consistent research programme, consolidating existing evidence and exploring new potential uses,would be very welcome.
К чему я все это? К тому, что по настоящее время "полезность" силибинина/силимарина все еще не является доказанной, хотя и существует определенный эвиденс.Herbal agents have been tried. Silymarin is the active ingredient in milk thistle, is a member of the flavonoids, and has shown remarkable hepatoprotective effects in experimental toxic liver injury. The precise mechanism of its hepatoprotective mediation is not known, but it is probably related to its antioxidant properties. In humans with mild alcoholic hepatitis, silymarin improves liver chemistry test results. In a single controlled trial among 170 subjects with alcoholic liver disease, silymarin reduced the liver-related deaths. However, in a recent meta-analysis of 13 clinical trials (about half of them double-blind), it was concluded that milk thistle did not significantly influence the clinical course of patients with alcoholic hepatitis.[SIZE=-1]47[/SIZE]